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Silver no_smiles Demethylation

CYP51DT

Dioscorea transversa CYP51D

Dioscoreaceae

Substrate reaction site Product reaction site MCS substructure diff highlighting · RDKit atom mapping
Substrate
4-desmethyl-24,25-dihydrolanosterol
PubChem ↗ Crowdsource substrate structure
CYP51DT
ΔMass: no_smiles Missing dual SMILES or RDKit not validated
Product
4α-methylcholesta-8,14-dien-3β-ol
PubChem ↗ CC(C)CCC[C@@H](C)[C@H]1CC=C2C3=C(CC[C@]12C)[C@@]4(C)CC[C@H](O)[…

Evidence trail

Excerpts are machine-extracted plain text for biochemical provenance. Follow DOI / PubMed links for the primary literature; publisher figures and PDF images are not displayed here.

Source text excerpt ation; ation; Purified recombinant CYP51Dt with CPRDt and NADPH; product identified by GC-MS.

Reaction & quality gates

Mechanism
Demethylation
Evidence type
In vitro
Confidence
High
Data tier
Silver
mass=no_smiles; incomplete_SMILES
Substrate class
Other
Product class
Other

Literature & public identifiers

PubMed
PMID:37142228 ↗
DOI
10.1016/j.jbc.2023.104768 ↗
UniProt
GenBank
NCBI TaxID
1518336 ↗

Characterization of the cholesterol biosynthetic pathway in Dioscorea transversa.