CYP716A262

Combinatorial optimization CYP716A

Substrate reaction site Product reaction site MCS substructure diff highlighting · RDKit atom mapping

Substrate

β-amyrin

PubChem ↗ [H][C@]12[C@H](O)C=C3[C@]4([H])CC(C)(C)CC[C@]4(C)CC[C@@]3(C)[C@…

CYP716A262

ΔMass: +29.9742 Da methyl_to_carboxyl(+29.9742)

Product

echinocystic acid

PubChem ↗ C[C@]12CC[C@@H](C([C@@H]1CC[C@@]3([C@@H]2CC=C4[C@]3(C[C@H]([C@@…

Evidence trail

Excerpts are machine-extracted plain text for biochemical provenance. Follow DOI / PubMed links for the primary literature; publisher figures and PDF images are not displayed here.

Source text excerpt ation; ation; CYP716A262 from Psammosilene tunicoides expressed in S. cerevisiae; EA production measured by LC/MS.

Reaction & quality gates

Mechanism: Oxidation
Evidence type: In vitro
Confidence: High
Data tier: Gold
Latin binomial + experiment + dual SMILES + ΔMass pass
Substrate class: Terpenoids
Product class: Organic acids

Literature & public identifiers

PubMed: PMID:37703999 ↗
DOI: 10.1016/j.ymben.2023.09.004 ↗
UniProt: —
GenBank: —
NCBI TaxID: —

Combinatorial optimization and spatial remodeling of CYPs to control product profile.

Evidence trail

Reaction & quality gates

Literature & public identifiers

Other reactions by this enzyme