CYP714E19

Combinatorial optimization CYP714E

Substrate reaction site Product reaction site MCS substructure diff highlighting · RDKit atom mapping

Substrate

β-amyrin

PubChem ↗ [H][C@]12[C@H](O)C=C3[C@]4([H])CC(C)(C)CC[C@]4(C)CC[C@@]3(C)[C@…

CYP714E19

ΔMass: +43.9534 Da mismatch

Product

quillaic acid

PubChem ↗ C[C@]12CC[C@@H]([C@@]([C@@H]1CC[C@@]3([C@@H]2CC=C4[C@]3(C[C@H](…

Evidence trail

Excerpts are machine-extracted plain text for biochemical provenance. Follow DOI / PubMed links for the primary literature; publisher figures and PDF images are not displayed here.

Source text excerpt ation; ation; CYP714E19 co-expressed with CYP72A567 and CYP716A262 leads to QA; multi-step oxidation.

Reaction & quality gates

Mechanism: Oxidation
Evidence type: In vitro
Confidence: High
Data tier: Silver
mass=mismatch
Substrate class: Terpenoids
Product class: Organic acids

Literature & public identifiers

PubMed: PMID:37703999 ↗
DOI: 10.1016/j.ymben.2023.09.004 ↗
UniProt: —
GenBank: —
NCBI TaxID: —

Combinatorial optimization and spatial remodeling of CYPs to control product profile.

Evidence trail

Reaction & quality gates

Literature & public identifiers

Other reactions by this enzyme