← Back to reactions
Silver no_smiles Other

DepF

Kinetic constants

Substrate reaction site Product reaction site MCS substructure diff highlighting · RDKit atom mapping
Substrate
depsidone 5
PubChem ↗ [H]C(=O)c1c(O)cc(C)c2c1Oc1cc3c(c(C)c1OC2=O)C(=O)CC(C)(C)O3
DepF
ΔMass: no_smiles Missing dual SMILES or RDKit not validated
Product
22
PubChem ↗ Crowdsource product structure

Evidence trail

Excerpts are machine-extracted plain text for biochemical provenance. Follow DOI / PubMed links for the primary literature; publisher figures and PDF images are not displayed here.

Source text excerpt Other; Other; DepF is a decarboxylase (amidohydrolase superfamily); removes C-10 carboxyl group. In vitro purified enzyme assay with 5 gave 22. Kinetic constants determined.

Reaction & quality gates

Mechanism
Other
Evidence type
In vitro
Confidence
High
Data tier
Silver
mass=no_smiles; incomplete_SMILES
Substrate class
Other
Product class
Other

Literature & public identifiers

PubMed
PMID:37719379 ↗
DOI
10.1016/j.apsb.2023.05.036 ↗
UniProt
—
GenBank
—
NCBI TaxID
—

Characterization of the depsidone gene cluster reveals etherification, decarboxylation and multiple halogenations as tailoring steps in depsidone assembly.