HmFLS1

Hypericum monogynum

Hypericaceae

Substrate reaction site Product reaction site MCS substructure diff highlighting · RDKit atom mapping

Substrate

dihydroquercetin

PubChem ↗ C1=CC(=C(C=C1[C@@H]2[C@H](C(=O)C3=C(C=C(C=C3O2)O)O)O)O)O

HmFLS1

ΔMass: -2.0157 Da ketone_formation(-2.0157)

Product

quercetin

PubChem ↗ C1=CC(=C(C=C1C2=C(C(=O)C3=C(C=C(C=C3O2)O)O)O)O)O

Evidence trail

Excerpts are machine-extracted plain text for biochemical provenance. Follow DOI / PubMed links for the primary literature; publisher figures and PDF images are not displayed here.

Source text excerpt ation; ation; In vitro and in vivo (with cofactors) conversion.

Reaction & quality gates

Mechanism: Ketone formation (-2.02 Da)
Evidence type: In vitro
Confidence: High
Data tier: Quarantine
non-CYP auxiliary enzyme (pathway partner, not cytochrome P450)
Substrate class: Phenylpropanoids
Product class: Phenylpropanoids

Literature & public identifiers

PubMed: PMID:37727703 ↗
DOI: 10.1093/hr/uhad166 ↗
UniProt: —
GenBank: —
NCBI TaxID: 684760 ↗

The parallel biosynthesis routes of hyperoside from naringenin in <i>Hypericum monogynum</i>.

Evidence trail

Reaction & quality gates

Literature & public identifiers

Other reactions by this enzyme