CYP71

Reinventing metabolic

Substrate reaction site Product reaction site MCS substructure diff highlighting · RDKit atom mapping

Substrate

2-hydroxy-3,4-dihydro-1,4-benzoxazin-3-one (HBOA)

PubChem ↗ OC1Oc2ccccc2NC1=O

CYP71

ΔMass: +15.9949 Da hydroxylation(+15.9949)

Product

2,4-dihydroxy-1,4-benzoxazin-3-one (DIBOA)

PubChem ↗ C1=CC=C2C(=C1)N(C(=O)C(O2)O)O

Evidence trail

Excerpts are machine-extracted plain text for biochemical provenance. Follow DOI / PubMed links for the primary literature; publisher figures and PDF images are not displayed here.

Source text excerpt ation; ation; LgBX5 from Lamium galeobdolon catalyzes N-hydroxylation of HBOA to DIBOA, demonstrated in N. benthamiana with ZmBx1-4+ZmBx8.

Reaction & quality gates

Mechanism: Hydroxylation (+15.99 Da)
Evidence type: In vivo
Confidence: High
Data tier: Gold
Latin binomial + experiment + dual SMILES + ΔMass pass
Substrate class: Other
Product class: Other

Literature & public identifiers

PubMed: PMID:37812727 ↗
DOI: 10.1073/pnas.2307981120 ↗
UniProt: Q0Z840 ↗
GenBank: —
NCBI TaxID: —

Reinventing metabolic pathways: Independent evolution of benzoxazinoids in flowering plants.