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Gold ΔMass ✓ Hydroxylation

C4H

Mentioned in

Substrate reaction site Product reaction site MCS substructure diff highlighting · RDKit atom mapping
Substrate
cinnamic acid
PubChem ↗ C1=CC=C(C=C1)/C=C/C(=O)O
C4H
ΔMass: +15.9949 Da hydroxylation(+15.9949)
Product
p-coumaric acid
PubChem ↗ C1=CC(=CC=C1/C=C/C(=O)O)O

Evidence trail

Excerpts are machine-extracted plain text for biochemical provenance. Follow DOI / PubMed links for the primary literature; publisher figures and PDF images are not displayed here.

Source text excerpt ation; ation; C4H is a cytochrome P450 monooxygenase complex that catalyzes the hydroxylation of the 4-position of cinnamic acid to produce coumaric acid. Mentioned in context of multiple plant species (P. sativum, Apium graveolens, A. thaliana, Zea mays) but no specific source organism Latin binomial provided in the text.

Reaction & quality gates

Mechanism
Hydroxylation (+15.99 Da)
Evidence type
In vitro
Confidence
High
Data tier
Gold
Latin binomial + experiment + dual SMILES + ΔMass pass
Substrate class
Phenylpropanoids
Product class
Phenylpropanoids

Literature & public identifiers

PubMed
PMID:38077428 ↗
DOI
10.7717/peerj.16508 ↗
UniProt
Q06Z32 ↗
GenBank
NCBI TaxID

Anabolic metabolism of autotoxic substance coumarins in plants.