CYP71AV1

Functions of CYP71A

Substrate reaction site Product reaction site MCS substructure diff highlighting · RDKit atom mapping

Substrate

amorpha-4,11-diene

PubChem ↗ C[C@@H]1CC[C@H]([C@@H]2[C@H]1CCC(=C2)C)C(=C)C

CYP71AV1

ΔMass: +15.9949 Da hydroxylation(+15.9949)

Product

artemisinic alcohol

PubChem ↗ C[C@@H]1CC[C@H]([C@@H]2[C@H]1CCC(=C2)C)C(=C)CO

Evidence trail

Excerpts are machine-extracted plain text for biochemical provenance. Follow DOI / PubMed links for the primary literature; publisher figures and PDF images are not displayed here.

Source text excerpt ation; ation; CYP71AV1 with CPR1 and CYB5 converts amorpha-4,11-diene to artemisinic alcohol; overexpression in A. annua increases artemisinin content 2.4-fold.

Reaction & quality gates

Mechanism: Hydroxylation (+15.99 Da)
Evidence type: In vitro
Confidence: High
Data tier: Gold
Latin binomial + experiment + dual SMILES + ΔMass pass
Substrate class: Other
Product class: Other

Literature & public identifiers

PubMed: PMID:38136596 ↗
DOI: 10.3390/biom13121725 ↗
UniProt: H6VZA6 ↗
GenBank: —
NCBI TaxID: —

Functions of Representative Terpenoids and Their Biosynthesis Mechanisms in Medicinal Plants.