AsCPS

Arthrinium sacchari

Substrate reaction site Product reaction site MCS substructure diff highlighting · RDKit atom mapping

Substrate

geranylgeranyl diphosphate

PubChem ↗ CC(=CCC/C(=C/CC/C(=C/CC/C(=C/COP(=O)(O)OP(=O)(O)O)/C)/C)/C)C

AsCPS

ΔMass: +0.0000 Da mismatch

Product

copalyl diphosphate

PubChem ↗ C/C(=C\COP(=O)(O)OP(=O)(O)O)/CC[C@H]1C(=C)CC[C@@H]2[C@@]1(CCCC2…

Evidence trail

Excerpts are machine-extracted plain text for biochemical provenance. Follow DOI / PubMed links for the primary literature; publisher figures and PDF images are not displayed here.

Source text excerpt ization; ization; AsCPS is a class II terpene cyclase from the fungus Arthrinium sacchari. The stereochemistry of CPP requires further verification.

Reaction & quality gates

Mechanism: Cyclization
Evidence type: In vitro
Confidence: High
Data tier: Quarantine
non-CYP auxiliary enzyme (pathway partner, not cytochrome P450)
Substrate class: Other
Product class: Other

Literature & public identifiers

PubMed: PMID:38590534 ↗
DOI: 10.3762/bjoc.20.65 ↗
UniProt: —
GenBank: —
NCBI TaxID: —

Genome mining of labdane-related diterpenoids: Discovery of the two-enzyme pathway leading to (-)-sandaracopimaradiene in the fungus <i>Arthrinium sacchari</i>.