CYP94N1V2

Veratrum californicum CYP94N

Melanthiaceae

Substrate reaction site Product reaction site MCS substructure diff highlighting · RDKit atom mapping

Substrate

22-hydroxycholesterol

PubChem ↗ C[C@@H]([C@H]1CC[C@@H]2[C@@]1(CC[C@H]3[C@H]2CC=C4[C@@]3(CC[C@@H…

CYP94N1V2

ΔMass: no_smiles Missing dual SMILES or RDKit not validated

Product

22-hydroxycholesterol-26-al

PubChem ↗ Crowdsource product structure

Evidence trail

Excerpts are machine-extracted plain text for biochemical provenance. Follow DOI / PubMed links for the primary literature; publisher figures and PDF images are not displayed here.

Source text excerpt ation; ation; CYP94N1v2 from Veratrum californicum; heterologous expression in Nicotiana benthamiana and Saccharomyces cerevisiae; catalyzes C26 oxidation of 22-hydroxycholesterol.

Reaction & quality gates

Mechanism: Oxidation
Evidence type: In vivo
Confidence: High
Data tier: Silver
mass=no_smiles; incomplete_SMILES
Substrate class: Steroids
Product class: Steroids

Literature & public identifiers

PubMed: PMID:39074544 ↗
DOI: 10.1016/j.ymben.2024.07.011 ↗
UniProt: A0A0F6PMN1 ↗
GenBank: —
NCBI TaxID: 50242 ↗

Verazine biosynthesis from simple sugars in engineered Saccharomyces cerevisiae.