CYP12

Biosynthesis and CYP12

Substrate reaction site Product reaction site MCS substructure diff highlighting · RDKit atom mapping

Substrate

α-humulene

PubChem ↗ C/C/1=C\CC(/C=C/C/C(=C/CC1)/C)(C)C

CYP12

ΔMass: +13.9793 Da mismatch

Product

rotundone

PubChem ↗ C[C@H]1CC[C@H](CC2=C1C(=O)C[C@@H]2C)C(=C)C

Evidence trail

Excerpts are machine-extracted plain text for biochemical provenance. Follow DOI / PubMed links for the primary literature; publisher figures and PDF images are not displayed here.

Source text excerpt ation; ation; UniProt: E3W9C4; also acts on α-guaiene, β-guaiene, δ-guaiene, and alloaromadendrene; efficiency 66±19% in C. reinhardtii plastid

Reaction & quality gates

Mechanism: Oxidation
Evidence type: In vivo
Confidence: High
Data tier: Silver
mass=mismatch
Substrate class: Other
Product class: Other

Literature & public identifiers

PubMed: PMID:39589357 ↗
DOI: 10.1002/cbic.202400902 ↗
UniProt: A0A0N7F296 ↗
GenBank: —
NCBI TaxID: —

Compartmentalized Sesquiterpenoid Biosynthesis and Functionalization in the Chlamydomonas reinhardtii Plastid.

Evidence trail

Reaction & quality gates

Literature & public identifiers

Other reactions by this enzyme