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Quarantine Literature error no_smiles Hydroxylation

CYP71A1

Oryza sativa CYP71A

Poaceae

Substrate reaction site Product reaction site MCS substructure diff highlighting · RDKit atom mapping
Substrate
serotonin
PubChem ↗ C1=CC2=C(C=C1O)C(=CN2)CCN
CYP71A1
ΔMass: no_smiles Missing dual SMILES or RDKit not validated
Product
5-hydroxyserotonin
PubChem ↗ Crowdsource product structure

Evidence trail

Excerpts are machine-extracted plain text for biochemical provenance. Follow DOI / PubMed links for the primary literature; publisher figures and PDF images are not displayed here.

Source text excerpt ation; ation; PMID=39769161, 正文第7页: 'the enzyme serotonyl 5-hydroxylase, encoded by the cytochrome P450 gene CYP71A1, is pivotal, converting serotonin into 5-hydroxyserotonin.' 证据来自BPH feeding诱导的体内实验,突变体分析显示CYP71A1缺失阻断5-hydroxyserotonin产生。

Reaction & quality gates

Mechanism
Hydroxylation
Evidence type
In vivo
Confidence
High
Data tier
Quarantine
Literature compound nomenclature error; manual curation required
Substrate class
Other
Product class
Other

Literature & public identifiers

PubMed
PMID:39769161 ↗
DOI
10.3390/ijms252413397 ↗
UniProt
A0A1L7H7V3 ↗
GenBank
NCBI TaxID
4530 ↗

Insight into Rice Resistance to the Brown Planthopper: Gene Cloning, Functional Analysis, and Breeding Applications.