HirF

Stereum hirsutum

Substrate reaction site Product reaction site MCS substructure diff highlighting · RDKit atom mapping

Substrate

C-5 monohydroxylated hirsutane (2)

PubChem ↗ Crowdsource substrate structure

HirF

ΔMass: no_smiles Missing dual SMILES or RDKit not validated

Product

C-5/C-7 dihydroxylated hirsutane (4)

PubChem ↗ Crowdsource product structure

Evidence trail

Excerpts are machine-extracted plain text for biochemical provenance. Follow DOI / PubMed links for the primary literature; publisher figures and PDF images are not displayed here.

Source text excerpt ation; ation; Heterologous expression in Aspergillus oryzae; AO-hirACF produced 4 as major product.

Reaction & quality gates

Mechanism: Hydroxylation
Evidence type: In vivo
Confidence: High
Data tier: Silver
mass=no_smiles; incomplete_SMILES
Substrate class: Other
Product class: Other

Literature & public identifiers

PubMed: PMID:40017741 ↗
DOI: 10.1021/jacsau.4c00983 ↗
UniProt: —
GenBank: —
NCBI TaxID: —

Biochemistry and Chemoinformatics Guided Classification of Hirsutane Sesquiterpenes Isolated from Mushroom.