RusF

Penicillium roqueforti

Substrate reaction site Product reaction site MCS substructure diff highlighting · RDKit atom mapping

Substrate

15a*

PubChem ↗ Crowdsource substrate structure

RusF

ΔMass: no_smiles Missing dual SMILES or RDKit not validated

Product

16a*

PubChem ↗ Crowdsource product structure

Evidence trail

Excerpts are machine-extracted plain text for biochemical provenance. Follow DOI / PubMed links for the primary literature; publisher figures and PDF images are not displayed here.

Source text excerpt ation; ation; RusF catalyzes two-step oxidation at C-8; 16a* is the 8-keto intermediate; proposed pathway.

Reaction & quality gates

Mechanism: Oxidation
Evidence type: In vivo
Confidence: High
Data tier: Silver
mass=no_smiles; incomplete_SMILES
Substrate class: Other
Product class: Other

Literature & public identifiers

PubMed: PMID:40029258 ↗
DOI: 10.1021/acs.orglett.5c00328 ↗
UniProt: W6R6G5 ↗
GenBank: —
NCBI TaxID: —

Formation of <i>N</i>-Hydroxyethylisoindolinone Derivatives in Fungi Requires Highly Coordinated Consecutive Oxidation Steps.