CYP107B1

Class of

Substrate reaction site Product reaction site MCS substructure diff highlighting · RDKit atom mapping

Substrate

gromomycin C

PubChem ↗ Crowdsource substrate structure

CYP107B1

ΔMass: no_smiles Missing dual SMILES or RDKit not validated

Product

gromomycin B

PubChem ↗ Crowdsource product structure

Evidence trail

Excerpts are machine-extracted plain text for biochemical provenance. Follow DOI / PubMed links for the primary literature; publisher figures and PDF images are not displayed here.

Source text excerpt ation; ation; GroI (CYP107B1) introduces a keto group at C-17 of gromomycin C to form gromomycin B, based on gene deletion and heterologous expression in S. albus/S. lividans.

Reaction & quality gates

Mechanism: Oxidation
Evidence type: In vivo
Confidence: High
Data tier: Silver
mass=no_smiles; incomplete_SMILES
Substrate class: Other
Product class: Other

Literature & public identifiers

PubMed: PMID:40106406 ↗
DOI: 10.1002/anie.202422270 ↗
UniProt: —
GenBank: —
NCBI TaxID: —

Gromomycins: An Unprecedented Class of Triterpene Antibiotics Produced by a Novel Biosynthetic Pathway.