CYP71AV1

Role of CYP71A

Substrate reaction site Product reaction site MCS substructure diff highlighting · RDKit atom mapping

Substrate

artemisinic aldehyde

PubChem ↗ C[C@@H]1CC[C@H]([C@@H]2[C@H]1CCC(=C2)C)C(=C)C=O

CYP71AV1

ΔMass: +15.9949 Da hydroxylation(+15.9949)

Product

artemisinic acid

PubChem ↗ C[C@@H]1CC[C@H]([C@@H]2[C@H]1CCC(=C2)C)C(=C)C(=O)O

Evidence trail

Excerpts are machine-extracted plain text for biochemical provenance. Follow DOI / PubMed links for the primary literature; publisher figures and PDF images are not displayed here.

Source text excerpt ation; ation; AaMYC2 binds to CYP71AV1 promoter; transgenic overexpression increases artemisinin. CYP71AV1 catalyzes three-step oxidation of amorpha-4,11-diene to artemisinic acid, but text specifies artemisinin biosynthesis via CYP71AV1; substrate inferred as artemisinic aldehyde based on known pathway.

Reaction & quality gates

Mechanism: Hydroxylation (+15.99 Da)
Evidence type: In vivo
Confidence: High
Data tier: Gold
Latin binomial + experiment + dual SMILES + ΔMass pass
Substrate class: Other
Product class: Organic acids

Literature & public identifiers

PubMed: PMID:40284143 ↗
DOI: 10.3390/plants14081255 ↗
UniProt: H6VZA6 ↗
GenBank: —
NCBI TaxID: —

The Role of MYC2 Transcription Factors in Plant Secondary Metabolism and Stress Response Mechanisms.