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Quarantine mismatch Cyclization

NsOSC2

Neopicrorhiza scrophulariiflora

Plantaginaceae

Substrate reaction site Product reaction site MCS substructure diff highlighting · RDKit atom mapping
Substrate
2,3-oxidosqualene
PubChem ↗ CC(=CCC/C(=C/CC/C(=C/CC/C=C(\C)/CC/C=C(\C)/CCC1C(O1)(C)C)/C)/C)C
NsOSC2
ΔMass: +0.0000 Da mismatch
Product
α-amyrin
PubChem ↗ C[C@@H]1CC[C@@]2(CC[C@@]3(C(=CC[C@H]4[C@]3(CC[C@@H]5[C@@]4(CC[C…

Evidence trail

Excerpts are machine-extracted plain text for biochemical provenance. Follow DOI / PubMed links for the primary literature; publisher figures and PDF images are not displayed here.

Source text excerpt ization; ization; Heterologous expression in yeast GIL77; GC-MS confirmed product.

Reaction & quality gates

Mechanism
Cyclization
Evidence type
In vitro
Confidence
High
Data tier
Quarantine
non-CYP auxiliary enzyme (pathway partner, not cytochrome P450)
Substrate class
Other
Product class
Terpenoids

Literature & public identifiers

PubMed
PMID:40431127 ↗
DOI
10.3390/plants14101562 ↗
UniProt
GenBank
NCBI TaxID
470706 ↗

Multi-Omics and Functional Insights into Triterpenoid Biosynthesis Pathways in <i>Neopicrorhiza scrophulariiflora</i> (Pennell) D.Y.Hong.