CYP90B94

Ornithogalum saundersiae CYP90B

Asparagaceae

Substrate reaction site Product reaction site MCS substructure diff highlighting · RDKit atom mapping

Substrate

cholesterol

PubChem ↗ C[C@H](CCCC(C)C)[C@H]1CC[C@@H]2[C@@]1(CC[C@H]3[C@H]2CC=C4[C@@]3…

CYP90B94

ΔMass: +15.9949 Da hydroxylation(+15.9949)

Product

22(R)-hydroxycholesterol

PubChem ↗ C[C@@H]([C@H]1CC[C@@H]2[C@@]1(CC[C@H]3[C@H]2CC=C4[C@@]3(CC[C@@H…

Evidence trail

Excerpts are machine-extracted plain text for biochemical provenance. Follow DOI / PubMed links for the primary literature; publisher figures and PDF images are not displayed here.

Source text excerpt ation; ation; In vitro activity confirmed in yeast microsomes and WAT11 microsomes; also in vivo in Nicotiana benthamiana.

Reaction & quality gates

Mechanism: Hydroxylation (+15.99 Da)
Evidence type: In vitro
Confidence: High
Data tier: Gold
Latin binomial + experiment + dual SMILES + ΔMass pass
Substrate class: Steroids
Product class: Steroids

Literature & public identifiers

PubMed: PMID:40545634 ↗
DOI: 10.1111/pbi.70080 ↗
UniProt: —
GenBank: —
NCBI TaxID: 484171 ↗

The clarification of two hydroxylation steps in the conversion of cholesterol to OSW-1 in Ornithogalum saundersiae.

Evidence trail

Reaction & quality gates

Literature & public identifiers

Other reactions by this enzyme