GAME6

Solanum lycopersicum

Solanaceae

Substrate reaction site Product reaction site MCS substructure diff highlighting · RDKit atom mapping

Substrate

cholesterol glucuronide

PubChem ↗ C[C@H](CCCC(C)C)[C@H]1CC[C@@H]2[C@@]1(CC[C@H]3[C@H]2CC=C4[C@@]3…

GAME6

ΔMass: no_smiles Missing dual SMILES or RDKit not validated

Product

22-hydroxycholesterol glucuronide

PubChem ↗ Crowdsource product structure

Evidence trail

Excerpts are machine-extracted plain text for biochemical provenance. Follow DOI / PubMed links for the primary literature; publisher figures and PDF images are not displayed here.

Source text excerpt ation; ation; SlGAME6 (CYP72A188) catalyzes C-22 hydroxylation; co-expression with other GAMEs in N. benthamiana.

Reaction & quality gates

Mechanism: Hydroxylation
Evidence type: In vivo
Confidence: High
Data tier: Silver
mass=no_smiles; incomplete_SMILES
Substrate class: Steroids
Product class: Steroids

Literature & public identifiers

PubMed: PMID:40684353 ↗
DOI: 10.1111/pbi.70213 ↗
UniProt: A0A3Q7H9W3 ↗
GenBank: —
NCBI TaxID: 4081 ↗

Complex engineering of Solanum alkaloids structural diversity in Nicotiana benthamiana.