DabC

Nitzschia navis

Substrate reaction site Product reaction site MCS substructure diff highlighting · RDKit atom mapping

Substrate

7'-carboxy-N-geranyl-L-glutamic acid

PubChem ↗ Crowdsource substrate structure

DabC

ΔMass: no_smiles Missing dual SMILES or RDKit not validated

Product

isodomoic acid B

PubChem ↗ C/C(=C\C/C=C(\C)/C(=O)O)/[C@H]1CN[C@@H]([C@H]1CC(=O)O)C(=O)O

Evidence trail

Excerpts are machine-extracted plain text for biochemical provenance. Follow DOI / PubMed links for the primary literature; publisher figures and PDF images are not displayed here.

Source text excerpt ization; ization; 体外酶活实验验证了NnvDabC催化7'-carboxy-L-NGG氧化环化生成isodomoic acid B。

Reaction & quality gates

Mechanism: Cyclization
Evidence type: In vitro
Confidence: High
Data tier: Silver
mass=no_smiles; incomplete_SMILES
Substrate class: Organic acids
Product class: Other

Literature & public identifiers

PubMed: PMID:41165336 ↗
DOI: 10.1128/mbio.02079-25 ↗
UniProt: —
GenBank: —
NCBI TaxID: —

Domoic acid biosynthesis and genome expansion in <i>Nitzschia navis-varingica</i>.