Quarantine
no_smiles
Reduction
Substrate reaction site
Product reaction site
MCS substructure diff highlighting · RDKit atom mapping
Substrate
3-dehydro-rauwolscine
PubChem ↗
COC(=O)[C@@H]1[C@H](CC[C@H]2[C@@H]1C[C@H]3C4=C(CCN3C2)C5=CC=CC=…
HYC3R
ΔMass: no_smiles
Missing dual SMILES or RDKit not validated
Evidence trail
Excerpts are machine-extracted plain text for biochemical provenance. Follow DOI / PubMed links for the primary literature; publisher figures and PDF images are not displayed here.
Source text excerpt ion; ion; Rauvolfia serpentina RsCAD7; purified recombinant protein; LC-MS/MS and NMR confirmed.
Reaction & quality gates
- Mechanism
- Reduction
- Evidence type
- In vitro
- Confidence
- High
- Data tier
- Quarantine
non-CYP auxiliary enzyme (pathway partner, not cytochrome P450) - Substrate class
- Other
- Product class
- Other
Literature & public identifiers
- PubMed
- PMID:41290611 ↗
- DOI
- 10.1038/s41467-025-65543-z ↗
- UniProt
- —
- GenBank
- —
- NCBI TaxID
- 545371 ↗
Ancient gene clusters govern the initiation of monoterpenoid indole alkaloid biosynthesis and C3 stereochemistry inversion.