C4H

The evidence

Substrate reaction site Product reaction site MCS substructure diff highlighting · RDKit atom mapping

Substrate

trans-cinnamic acid

PubChem ↗ C1=CC=C(C=C1)/C=C/C(=O)O

C4H

ΔMass: +15.9949 Da hydroxylation(+15.9949)

Product

p-coumaric acid

PubChem ↗ C1=CC(=CC=C1/C=C/C(=O)O)O

Evidence trail

Excerpts are machine-extracted plain text for biochemical provenance. Follow DOI / PubMed links for the primary literature; publisher figures and PDF images are not displayed here.

Source text excerpt ation; ation; C4H is a cytochrome P450 monooxygenase; the reaction is described in the text as the second committed step in the phenylpropanoid pathway, converting trans-cinnamic acid to p-coumaric acid. The evidence is based on general biochemical characterization, but no specific plant source is mentioned in the abstract or methods for this enzyme.

Reaction & quality gates

Mechanism: Hydroxylation (+15.99 Da)
Evidence type: In vitro
Confidence: High
Data tier: Gold
Latin binomial + experiment + dual SMILES + ΔMass pass
Substrate class: Phenylpropanoids
Product class: Phenylpropanoids

Literature & public identifiers

PubMed: PMID:41296446 ↗
DOI: 10.3390/cimb47110942 ↗
UniProt: Q06Z32 ↗
GenBank: —
NCBI TaxID: —

Recent Advances in Biosynthesis and Bioactivity of Plant Caffeoylquinic Acids.