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Silver no_smiles Oxidation

SBE

Tabernanthe iboga

Apocynaceae

Substrate reaction site Product reaction site MCS substructure diff highlighting · RDKit atom mapping
Substrate
19Z-geissoschizine
PubChem ↗ C/C=C/1\CN2CCC3=C([C@@H]2C[C@@H]1/C(=C/O)/C(=O)OC)NC4=CC=CC=C34
SBE
ΔMass: no_smiles Missing dual SMILES or RDKit not validated
Product
19Z-tetradehydrogeissoschizine
PubChem ↗ Crowdsource product structure

Evidence trail

Excerpts are machine-extracted plain text for biochemical provenance. Follow DOI / PubMed links for the primary literature; publisher figures and PDF images are not displayed here.

Source text excerpt ation; ation; TiSBE in yeast microsomes; product consistent with m/z 349.1548 and Z-shifted retention time.

Reaction & quality gates

Mechanism
Oxidation
Evidence type
In vitro
Confidence
High
Data tier
Silver
mass=no_smiles; incomplete_SMILES
Substrate class
Other
Product class
Other

Literature & public identifiers

PubMed
PMID:41478566 ↗
DOI
10.1016/j.jbc.2025.111120 ↗
UniProt
PX547883 ↗
GenBank
PX547883 ↗
NCBI TaxID
141617 ↗

Conserved early steps of stemmadenine biosynthesis.