CYP80G2

Biosynthesis of CYP80G

Substrate reaction site Product reaction site MCS substructure diff highlighting · RDKit atom mapping

Substrate

(S)-reticuline

PubChem ↗ CN1CCC2=CC(=C(C=C2[C@@H]1CC3=CC(=C(C=C3)OC)O)O)OC

CYP80G2

ΔMass: -2.0157 Da fallback:~-2 Da (成酮/脱氢)

Product

corytuberine

PubChem ↗ CN1CCC2=CC(=C(C3=C2[C@@H]1CC4=C3C(=C(C=C4)OC)O)O)OC

Evidence trail

Excerpts are machine-extracted plain text for biochemical provenance. Follow DOI / PubMed links for the primary literature; publisher figures and PDF images are not displayed here.

Source text excerpt ization; ization; PMID=41776991, 正文第4页: 'CjCYP80G2 and AcCYP80G7' 催化C2′–C8 coupling生成corytuberine。

Reaction & quality gates

Mechanism: Ketone formation (-2.02 Da)
Evidence type: In vitro
Confidence: High
Data tier: Gold
Latin binomial + experiment + dual SMILES + ΔMass pass
Substrate class: Other
Product class: Other

Literature & public identifiers

PubMed: PMID:41776991 ↗
DOI: 10.1016/j.xplc.2026.101786 ↗
UniProt: A8CDR5 ↗
GenBank: —
NCBI TaxID: —

Biosynthesis of benzylisoquinoline alkaloids and its evolution in plants.