CYP719A22

Biosynthesis of CYP719A

Substrate reaction site Product reaction site MCS substructure diff highlighting · RDKit atom mapping

Substrate

caaverine

PubChem ↗ COC1=C(C2=C3[C@@H](CC4=CC=CC=C42)NCCC3=C1)O

CYP719A22

ΔMass: -2.0157 Da fallback:~-2 Da (成酮/脱氢)

Product

anonaine

PubChem ↗ C1CN[C@@H]2CC3=CC=CC=C3C4=C2C1=CC5=C4OCO5

Evidence trail

Excerpts are machine-extracted plain text for biochemical provenance. Follow DOI / PubMed links for the primary literature; publisher figures and PDF images are not displayed here.

Source text excerpt ization; ization; PMID=41776991, 正文第8页: 'NnCYP719A22 from N. nucifera catalyzes the formation of a methylenedioxy bridge between C1 and C2 in aporphine-type alkaloids, converting caaverine to anonaine'。

Reaction & quality gates

Mechanism: Ketone formation (-2.02 Da)
Evidence type: In vitro
Confidence: High
Data tier: Gold
Latin binomial + experiment + dual SMILES + ΔMass pass
Substrate class: Other
Product class: Other

Literature & public identifiers

PubMed: PMID:41776991 ↗
DOI: 10.1016/j.xplc.2026.101786 ↗
UniProt: —
GenBank: —
NCBI TaxID: —

Biosynthesis of benzylisoquinoline alkaloids and its evolution in plants.