CYP71D180

Vitex agnus-castus CYP71D

Lamiaceae

Substrate reaction site Product reaction site MCS substructure diff highlighting · RDKit atom mapping

Substrate

clerodane-type diterpene precursors

PubChem ↗ Crowdsource substrate structure

CYP71D180

ΔMass: no_smiles Missing dual SMILES or RDKit not validated

Product

vitexilactone

PubChem ↗ C[C@@H]1C[C@H]([C@@H]2[C@@]([C@]1(CCC3=CC(=O)OC3)O)(CCCC2(C)C)C…

Evidence trail

Excerpts are machine-extracted plain text for biochemical provenance. Follow DOI / PubMed links for the primary literature; publisher figures and PDF images are not displayed here.

Source text excerpt ation; ation; Vitex agnus-castus; multi-step hydroxylation at C-6b and C-16.

Reaction & quality gates

Mechanism: Hydroxylation
Evidence type: In vitro
Confidence: High
Data tier: Silver
mass=no_smiles; incomplete_SMILES
Substrate class: Terpenoids
Product class: Other

Literature & public identifiers

PubMed: PMID:41799975 ↗
DOI: 10.3389/fpls.2026.1765290 ↗
UniProt: P0DO38 ↗
GenBank: —
NCBI TaxID: 54477 ↗

Cytochrome P450 gene family: cross-pathway functional conservation, novel catalytic reactions, and synthetic biology-driven applications in plant secondary metabolism.