CYP81Q58

Hemsleya ellipsoidea

Cucurbitaceae

Substrate reaction site Product reaction site MCS substructure diff highlighting · RDKit atom mapping

Substrate

cucurbitacin B

PubChem ↗ CC(=O)OC(C)(C)/C=C/C(=O)[C@@](C)([C@H]1[C@@H](C[C@@]2([C@@]1(CC…

CYP81Q58

ΔMass: no_smiles Missing dual SMILES or RDKit not validated

Product

2-hydroxycucurbitacin B

PubChem ↗ Crowdsource product structure

Evidence trail

Excerpts are machine-extracted plain text for biochemical provenance. Follow DOI / PubMed links for the primary literature; publisher figures and PDF images are not displayed here.

Source text excerpt ation; ation; Homolog of Cs180, which catalyzes C2 hydroxylation of cucurbitacin B in cucumber; functional characterization in H. ellipsoidea inferred by sequence similarity.

Reaction & quality gates

Mechanism: Hydroxylation
Evidence type: In vitro
Confidence: High
Data tier: Silver
mass=no_smiles; incomplete_SMILES
Substrate class: Other
Product class: Other

Literature & public identifiers

PubMed: PMID:42004501 ↗
DOI: 10.1093/hr/uhaf363 ↗
UniProt: —
GenBank: —
NCBI TaxID: 447114 ↗

Multiomics analysis of <i>Hemsleya ellipsoidea</i> reveals genome evolution and specialized cucurbitacin IIa biosynthesis in a medicinal Cucurbitaceae species.

Evidence trail

Reaction & quality gates

Literature & public identifiers

Other reactions by this enzyme