CYP71AV1

Stable heterologous CYP71A

Substrate reaction site Product reaction site MCS substructure diff highlighting · RDKit atom mapping

Substrate

amorpha-4,11-diene

PubChem ↗ C[C@@H]1CC[C@H]([C@@H]2[C@H]1CCC(=C2)C)C(=C)C

CYP71AV1

ΔMass: +15.9949 Da hydroxylation(+15.9949)

Product

artemisinic alcohol

PubChem ↗ C[C@@H]1CC[C@H]([C@@H]2[C@H]1CCC(=C2)C)C(=C)CO

Evidence trail

Excerpts are machine-extracted plain text for biochemical provenance. Follow DOI / PubMed links for the primary literature; publisher figures and PDF images are not displayed here.

Source text excerpt ation; ation; Table 1: Overexpression in Nicotiana tabacum; CYP71AV1 (amorphadiene oxidase) from Artemisia annua. Source organism not explicitly stated in abstract or methods for this specific reaction, but enzyme is from A. annua. NEEDS_SALVAGE due to lack of explicit Latin binomial in provided text.

Reaction & quality gates

Mechanism: Hydroxylation (+15.99 Da)
Evidence type: In vivo
Confidence: High
Data tier: Gold
Latin binomial + experiment + dual SMILES + ΔMass pass
Substrate class: Other
Product class: Other

Literature & public identifiers

PubMed: PMID:25852702 ↗
DOI: 10.3389/fpls.2015.00129 ↗
UniProt: H6VZA6 ↗
GenBank: —
NCBI TaxID: —

Stable heterologous expression of biologically active terpenoids in green plant cells.

Evidence trail

Reaction & quality gates

Literature & public identifiers

Other reactions by this enzyme