CYP76AH15

Coleus forskohlii CYP76A

Lamiaceae

Substrate reaction site Product reaction site MCS substructure diff highlighting · RDKit atom mapping

Substrate

13R-manoyl oxide

PubChem ↗ C[C@@]1(CC[C@@H]2[C@]3(CCCC([C@@H]3CC[C@]2(O1)C)(C)C)C)C=C

CYP76AH15

ΔMass: no_smiles Missing dual SMILES or RDKit not validated

Product

11-oxo-13R-manoyl oxide

PubChem ↗ Crowdsource product structure

Evidence trail

Excerpts are machine-extracted plain text for biochemical provenance. Follow DOI / PubMed links for the primary literature; publisher figures and PDF images are not displayed here.

Source text excerpt ation; ation; Yeast cells expressing CYP76AH15 and producing 13R-manoyl oxide; product identified by GC-MS.

Reaction & quality gates

Mechanism: Oxidation
Evidence type: In vivo
Confidence: High
Data tier: Silver
mass=no_smiles; incomplete_SMILES
Substrate class: Other
Product class: Other

Literature & public identifiers

PubMed: PMID:30453976 ↗
DOI: 10.1186/s12934-018-1027-3 ↗
UniProt: KT382358 ↗
GenBank: KT382358 ↗
NCBI TaxID: 41228 ↗

Engineering of CYP76AH15 can improve activity and specificity towards forskolin biosynthesis in yeast.

Evidence trail

Reaction & quality gates

Literature & public identifiers

Other reactions by this enzyme