TgTPS2

Tectona grandis

Lamiaceae

Substrate reaction site Product reaction site MCS substructure diff highlighting · RDKit atom mapping

Substrate

ent-copalyldiphosphate

PubChem ↗ Crowdsource substrate structure

TgTPS2

ΔMass: no_smiles Missing dual SMILES or RDKit not validated

Product

ent-kaurene

PubChem ↗ C[C@@]12CCCC([C@H]1CC[C@]34[C@H]2CC[C@H](C3)C(=C)C4)(C)C

Evidence trail

Excerpts are machine-extracted plain text for biochemical provenance. Follow DOI / PubMed links for the primary literature; publisher figures and PDF images are not displayed here.

Source text excerpt ization; ization; Transient expression in Nicotiana benthamiana; converts ent-copalyldiphosphate to ent-kaurene.

Reaction & quality gates

Mechanism: Cyclization
Evidence type: In vivo
Confidence: High
Data tier: Quarantine
non-CYP auxiliary enzyme (pathway partner, not cytochrome P450)
Substrate class: Other
Product class: Terpenoids

Literature & public identifiers

PubMed: PMID:30698701 ↗
DOI: 10.1093/gigascience/giz005 ↗
UniProt: —
GenBank: —
NCBI TaxID: 41396 ↗

A chromosomal-scale genome assembly of Tectona grandis reveals the importance of tandem gene duplication and enables discovery of genes in natural product biosynthetic pathways.