LtmJ

Unknown

Substrate reaction site Product reaction site MCS substructure diff highlighting · RDKit atom mapping

Substrate

paspaline (1)

PubChem ↗ C[C@@]12CC[C@H](O[C@H]1CC[C@]3([C@H]2CC[C@@H]4[C@@]3(C5=C(C4)C6…

LtmJ

ΔMass: no_smiles Missing dual SMILES or RDKit not validated

Product

terpendole E (5)

PubChem ↗ Crowdsource product structure

Evidence trail

Excerpts are machine-extracted plain text for biochemical provenance. Follow DOI / PubMed links for the primary literature; publisher figures and PDF images are not displayed here.

Source text excerpt ation; ation; LtmJ is a P450 monooxygenase; the reaction is part of the lolitrem biosynthetic pathway reconstituted in Aspergillus oryzae.

Reaction & quality gates

Mechanism: Oxidation
Evidence type: In vivo
Confidence: High
Data tier: Quarantine
non-CYP auxiliary enzyme (pathway partner, not cytochrome P450)
Substrate class: Other
Product class: Other

Literature & public identifiers

PubMed: PMID:32677206 ↗
DOI: 10.1002/anie.202007280 ↗
UniProt: —
GenBank: —
NCBI TaxID: —

Biosynthesis of Indole Diterpene Lolitrems: Radical-Induced Cyclization of an Epoxyalcohol Affording a Characteristic Lolitremane Skeleton.