CYP71D373

Salvia miltiorrhiza CYP71D

Lamiaceae

Substrate reaction site Product reaction site MCS substructure diff highlighting · RDKit atom mapping

Substrate

PubChem ↗ C=CCN(C)CCCCCCOc1ccc(C(=O)c2ccc(Br)cc2)c(F)c1.O=C(O)/C=C/C(=O)O

CYP71D373

ΔMass: no_smiles Missing dual SMILES or RDKit not validated

Product

16-hydroxy Ro

PubChem ↗ Crowdsource product structure

Evidence trail

Excerpts are machine-extracted plain text for biochemical provenance. Follow DOI / PubMed links for the primary literature; publisher figures and PDF images are not displayed here.

Source text excerpt ation; ation; Minor product from CYP71D373 with Ro (5), identified as 16-hydroxy derivative (9) by comparison to authentic standard.

Reaction & quality gates

Mechanism: Hydroxylation
Evidence type: In vitro
Confidence: High
Data tier: Silver
mass=no_smiles; incomplete_SMILES
Substrate class: Other
Product class: Other

Literature & public identifiers

PubMed: PMID:33514704 ↗
DOI: 10.1038/s41467-021-20959-1 ↗
UniProt: —
GenBank: —
NCBI TaxID: 226208 ↗

Expansion within the CYP71D subfamily drives the heterocyclization of tanshinones synthesis in Salvia miltiorrhiza.

Evidence trail

Reaction & quality gates

Literature & public identifiers

Other reactions by this enzyme