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Silver mismatch Oxidation

CYP726A20

Jatropha curcas CYP726A

Euphorbiaceae

Substrate reaction site Product reaction site MCS substructure diff highlighting · RDKit atom mapping
Substrate
casbene
PubChem ↗ C/C/1=C\CC/C(=C/C2C(C2(C)C)CC/C(=C/CC1)/C)/C
CYP726A20
ΔMass: +43.9534 Da mismatch
Product
6-hydroxy-5-ketocasbene
PubChem ↗ C[C@H]1C[C@]2([C@H](C1=O)/C=C(/CC[C@H]3[C@H](C3(C)C)/C=C(/C2=O)…

Evidence trail

Excerpts are machine-extracted plain text for biochemical provenance. Follow DOI / PubMed links for the primary literature; publisher figures and PDF images are not displayed here.

Source text excerpt ation; ation; Transient expression in N. benthamiana; JcCYP726A20 oxidizes casbene; 6-hydroxy-5-ketocasbene detected as intermediate.

Reaction & quality gates

Mechanism
Oxidation
Evidence type
In vivo
Confidence
High
Data tier
Silver
mass=mismatch
Substrate class
Other
Product class
Other

Literature & public identifiers

PubMed
PMID:33657678 ↗
DOI
10.1111/pbi.13574 ↗
UniProt
A0A067LCX8 ↗
GenBank
NCBI TaxID
180498 ↗

Developing a Nicotiana benthamiana transgenic platform for high-value diterpene production and candidate gene evaluation.