DrtB

Biosynthesis of

Substrate reaction site Product reaction site MCS substructure diff highlighting · RDKit atom mapping

Substrate

farnesyl pyrophosphate

PubChem ↗ CC(=CCC/C(=C/CC/C(=C/COP(=O)(O)OP(=O)(O)O)/C)/C)C

DrtB

ΔMass: -159.9327 Da mismatch

Product

drimenol

PubChem ↗ CC1=CC[C@@H]2[C@@]([C@H]1CO)(CCCC2(C)C)C

Evidence trail

Excerpts are machine-extracted plain text for biochemical provenance. Follow DOI / PubMed links for the primary literature; publisher figures and PDF images are not displayed here.

Source text excerpt ization; ization; 纯化DrtB与FPP体外孵育合成drimenol；体内异源表达也证实。

Reaction & quality gates

Mechanism: Cyclization
Evidence type: In vitro
Confidence: High
Data tier: Quarantine
non-CYP auxiliary enzyme (pathway partner, not cytochrome P450)
Substrate class: Other
Product class: Other

Literature & public identifiers

PubMed: PMID:34468074 ↗
DOI: 10.1002/anie.202108970 ↗
UniProt: —
GenBank: —
NCBI TaxID: —

Biosynthesis of Fungal Drimane-Type Sesquiterpene Esters.