CYP87D18

Siraitia grosvenorii CYP87D

Cucurbitaceae

Substrate reaction site Product reaction site MCS substructure diff highlighting · RDKit atom mapping

Substrate

24,25-dihydroxycucurbitadienol

PubChem ↗ Crowdsource substrate structure

CYP87D18

ΔMass: no_smiles Missing dual SMILES or RDKit not validated

Product

mogrol

PubChem ↗ C[C@H](CC[C@H](C(C)(C)O)O)[C@H]1CC[C@@]2([C@@]1(C[C@H]([C@@]3([…

Evidence trail

Excerpts are machine-extracted plain text for biochemical provenance. Follow DOI / PubMed links for the primary literature; publisher figures and PDF images are not displayed here.

Source text excerpt ation; ation; CYP87D18 catalyzes the C-11 hydroxylation of 24,25-dihydroxycucurbitadienol to form mogrol, verified by heterologous expression in S. cerevisiae and LC-MS detection.

Reaction & quality gates

Mechanism: Hydroxylation
Evidence type: In vivo
Confidence: High
Data tier: Silver
mass=no_smiles; incomplete_SMILES
Substrate class: Other
Product class: Other

Literature & public identifiers

PubMed: PMID:35711645 ↗
DOI: 10.3389/fbioe.2022.919526 ↗
UniProt: K7NBR2 ↗
GenBank: —
NCBI TaxID: 190515 ↗

Construction and Optimization of the <i>de novo</i> Biosynthesis Pathway of Mogrol in <i>Saccharomyces Cerevisiae</i>.

Evidence trail

Reaction & quality gates

Literature & public identifiers

Other reactions by this enzyme