CYP71AH44

Strychnos nux CYP71A

Loganiaceae

Substrate reaction site Product reaction site MCS substructure diff highlighting · RDKit atom mapping

Substrate

β-colubrine

PubChem ↗ COC1=CC2=C(C=C1)N3[C@@H]4[C@]25CCN6[C@H]5C[C@@H]7[C@H]4[C@H](CC…

CYP71AH44

ΔMass: no_smiles Missing dual SMILES or RDKit not validated

Product

11-deMe brucine

PubChem ↗ Crowdsource product structure

Evidence trail

Excerpts are machine-extracted plain text for biochemical provenance. Follow DOI / PubMed links for the primary literature; publisher figures and PDF images are not displayed here.

Source text excerpt ation; ation; Snv11H; also produces brucine when combined with SnvOMT

Reaction & quality gates

Mechanism: Hydroxylation
Evidence type: In vivo
Confidence: High
Data tier: Silver
mass=no_smiles; incomplete_SMILES
Substrate class: Other
Product class: Other

Literature & public identifiers

PubMed: PMID:35794473 ↗
DOI: 10.1038/s41586-022-04950-4 ↗
UniProt: —
GenBank: —
NCBI TaxID: 28545 ↗

Biosynthesis of strychnine.