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Quarantine mismatch Isomerization

KSI

NEEDS_SALVAGE

Substrate reaction site Product reaction site MCS substructure diff highlighting · RDKit atom mapping
Substrate
(+)-cis-isopulegone
PubChem ↗ C[C@@H]1CC[C@@H](C(=O)C1)C(=C)C
KSI
ΔMass: +0.0000 Da mismatch
Product
(+)-pulegone
PubChem ↗ C[C@@H]1CCC(=C(C)C)C(=O)C1

Evidence trail

Excerpts are machine-extracted plain text for biochemical provenance. Follow DOI / PubMed links for the primary literature; publisher figures and PDF images are not displayed here.

Source text excerpt ization; ization; KSI is steroid isomerase from Pseudomonas putida; expressed in S. cerevisiae; product detected by GC-MS.

Reaction & quality gates

Mechanism
Isomerization
Evidence type
In vivo
Confidence
High
Data tier
Quarantine
non-CYP auxiliary enzyme (pathway partner, not cytochrome P450)
Substrate class
Other
Product class
Other

Literature & public identifiers

PubMed
PMID:36135706 ↗
DOI
10.3390/jof8090982 ↗
UniProt
A0A1D1Z028 ↗
GenBank
NCBI TaxID

Engineered <i>Saccharomyces cerevisiae</i> for the <i>De Novo</i> Biosynthesis of (-)-Menthol.