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Bronze no_smiles Hydroxylation

CYP98A3

Cistanche tubulosa CYP98A

Orobanchaceae

Substrate reaction site Product reaction site MCS substructure diff highlighting · RDKit atom mapping
Substrate
p-coumaroyl shikimic acid
PubChem ↗ Crowdsource substrate structure
CYP98A3
ΔMass: no_smiles Missing dual SMILES or RDKit not validated
Product
caffeoyl shikimic acid
PubChem ↗ O=C(/C=C/c1ccc(O)c(O)c1)O[C@@H]1CC(C(=O)O)=C[C@@H](O)[C@H]1O

Evidence trail

Excerpts are machine-extracted plain text for biochemical provenance. Follow DOI / PubMed links for the primary literature; publisher figures and PDF images are not displayed here.

Source text excerpt ation; ation; CYP98A3 also catalyzes the hydroxylation of p-coumaroyl shikimic acid to caffeoyl shikimic acid. The paper mentions this activity, but no direct enzyme assay is provided.

Reaction & quality gates

Mechanism
Hydroxylation
Evidence type
Pathway_inference
Confidence
Medium
Data tier
Bronze
evidence=Pathway_inference
Substrate class
Organic acids
Product class
Organic acids

Literature & public identifiers

PubMed
PMID:36209069 ↗
DOI
10.1186/s12864-022-08921-x ↗
UniProt
A0A5P8H637 ↗
GenBank
NCBI TaxID
161397 ↗

De novo full length transcriptome analysis and gene expression profiling to identify genes involved in phenylethanol glycosides biosynthesis in Cistanche tubulosa.