CYP76AH1

Recombinant yeast CYP76A

Substrate reaction site Product reaction site MCS substructure diff highlighting · RDKit atom mapping

Substrate

sugiol

PubChem ↗ CC(C)C1=C(C=C2C(=C1)C(=O)C[C@@H]3[C@@]2(CCCC3(C)C)C)O

CYP76AH1

ΔMass: +15.9949 Da hydroxylation(+15.9949)

Product

11-hydroxysugiol

PubChem ↗ CC(C)C1=C(C(=C2C(=C1)C(=O)C[C@@H]3[C@@]2(CCCC3(C)C)C)O)O

Evidence trail

Excerpts are machine-extracted plain text for biochemical provenance. Follow DOI / PubMed links for the primary literature; publisher figures and PDF images are not displayed here.

Source text excerpt ation; ation; Recombinant yeast microsomal assay; minor product for most CYP76AH1, but major for some variants (e.g., SflCYP76AH3, ShoCYP76AH3, SprCYP76AH3-01, SprCYP76AH3-02, SseCYP76AH24).

Reaction & quality gates

Mechanism: Hydroxylation (+15.99 Da)
Evidence type: In vitro
Confidence: Medium
Data tier: Gold
Latin binomial + experiment + dual SMILES + ΔMass pass
Substrate class: Other
Product class: Other

Literature & public identifiers

PubMed: PMID:37375266 ↗
DOI: 10.3390/molecules28124711 ↗
UniProt: KT382349 ↗
GenBank: KT382349 ↗
NCBI TaxID: —

Functional Study and Efficient Catalytic Element Mining of CYP76AHs in <i>Salvia</i> Plants.

Evidence trail

Reaction & quality gates

Literature & public identifiers

Other reactions by this enzyme