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Silver no_smiles Glycosylation

BbGT1

Spenglerase drives

Substrate reaction site Product reaction site MCS substructure diff highlighting · RDKit atom mapping
Substrate
6-hydroxy-3-carbomethoxy-1-acetyl-β-carboline
PubChem ↗ COC(=O)c1cc2c([nH]c3ccc(O)cc23)c(n1)C(C)=O
BbGT1
ΔMass: no_smiles Missing dual SMILES or RDKit not validated
Product
bassicarboside F
PubChem ↗ Crowdsource product structure

Evidence trail

Excerpts are machine-extracted plain text for biochemical provenance. Follow DOI / PubMed links for the primary literature; publisher figures and PDF images are not displayed here.

Source text excerpt ation; ation; BbGT1/BbMT1 mediate methylglucosylation of 6-hydroxy-3-carbomethoxy-AβC to BCS F; verified by yeast feeding.

Reaction & quality gates

Mechanism
Glycosylation
Evidence type
In vitro
Confidence
High
Data tier
Silver
mass=no_smiles; incomplete_SMILES
Substrate class
Other
Product class
Other

Literature & public identifiers

PubMed
PMID:37467272 ↗
DOI
10.1073/pnas.2303327120 ↗
UniProt
GenBank
NCBI TaxID

A bacterial-like Pictet-Spenglerase drives the evolution of fungi to produce β-carboline glycosides together with separate genes.