CYP716A418

Erysimum cheiranthoides CYP716A

Brassicaceae

Substrate reaction site Product reaction site MCS substructure diff highlighting · RDKit atom mapping

Substrate

digitoxigenin

PubChem ↗ C[C@]12CC[C@@H](C[C@H]1CC[C@@H]3[C@@H]2CC[C@]4([C@@]3(CC[C@@H]4…

CYP716A418

ΔMass: no_smiles Missing dual SMILES or RDKit not validated

Product

cannogenol

PubChem ↗ Crowdsource product structure

Evidence trail

Excerpts are machine-extracted plain text for biochemical provenance. Follow DOI / PubMed links for the primary literature; publisher figures and PDF images are not displayed here.

Source text excerpt ation; ation; Knockout lines hyperaccumulate digitoxigenin glycosides and lack cannogenol/cannogenin/strophanthidin, indicating C19 hydroxylation.

Reaction & quality gates

Mechanism: Hydroxylation
Evidence type: In vivo
Confidence: High
Data tier: Silver
mass=no_smiles; incomplete_SMILES
Substrate class: Other
Product class: Other

Literature & public identifiers

PubMed: PMID:38229566 ↗
DOI: 10.1111/nph.19534 ↗
UniProt: —
GenBank: —
NCBI TaxID: 330168 ↗

Cardiac glycosides protect wormseed wallflower (Erysimum cheiranthoides) against some, but not all, glucosinolate-adapted herbivores.