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Quarantine mismatch Glycosylation

UGT71C4

Gossypium hirsutum

Malvaceae

Substrate reaction site Product reaction site MCS substructure diff highlighting · RDKit atom mapping
Substrate
naringenin
PubChem ↗ C1[C@H](OC2=CC(=CC(=C2C1=O)O)O)C3=CC=C(C=C3)O
UGT71C4
ΔMass: +162.0528 Da mismatch
Product
naringenin-7-O-glucoside
PubChem ↗ C1C(OC2=CC(=CC(=C2C1=O)O)O[C@H]3C([C@@H]([C@@H](C(O3)CO)O)O)O)C…

Evidence trail

Excerpts are machine-extracted plain text for biochemical provenance. Follow DOI / PubMed links for the primary literature; publisher figures and PDF images are not displayed here.

Source text excerpt ation; ation; Recombinant UGT71C4 protein was purified and in vitro binding assays performed; HPLC/UPLC-ESI-MS analysis confirmed conversion of naringenin to naringenin-7-O-glucoside (N7G).

Reaction & quality gates

Mechanism
Glycosylation
Evidence type
In vitro
Confidence
High
Data tier
Quarantine
non-CYP auxiliary enzyme (pathway partner, not cytochrome P450)
Substrate class
Phenylpropanoids
Product class
Phenylpropanoids

Literature & public identifiers

PubMed
PMID:38689494 ↗
DOI
10.1016/j.xplc.2024.100938 ↗
UniProt
A0A2I0W359 ↗
GenBank
NCBI TaxID
3635 ↗

UDP-glucosyltransferase 71C4 controls the flux of phenylpropanoid metabolism to shape cotton seed development.