CYP725A4

Engineering cyanobacteria CYP725A

Substrate reaction site Product reaction site MCS substructure diff highlighting · RDKit atom mapping

Substrate

taxadiene

PubChem ↗ CC1=C2CC[C@@]3(CCC=C([C@H]3C[C@@H](C2(C)C)CC1)C)C

CYP725A4

ΔMass: no_smiles Missing dual SMILES or RDKit not validated

Product

taxadiene-5α-ol

PubChem ↗ Crowdsource product structure

Evidence trail

Excerpts are machine-extracted plain text for biochemical provenance. Follow DOI / PubMed links for the primary literature; publisher figures and PDF images are not displayed here.

Source text excerpt ation; ation; 本文在Synechocystis sp. PCC 6803中异源表达CYP725A4（T5αH）和CPR，催化taxadiene生成taxadiene-5α-ol（T5α-ol），证据来自GC-MS检测。

Reaction & quality gates

Mechanism: Hydroxylation
Evidence type: In vivo
Confidence: High
Data tier: Silver
mass=no_smiles; incomplete_SMILES
Substrate class: Other
Product class: Other

Literature & public identifiers

PubMed: PMID:39014505 ↗
DOI: 10.1186/s13068-024-02555-9 ↗
UniProt: —
GenBank: —
NCBI TaxID: —

Engineering cyanobacteria as a new platform for producing taxol precursors directly from carbon dioxide.