GAME12

Solanum lycopersicum

Solanaceae

Substrate reaction site Product reaction site MCS substructure diff highlighting · RDKit atom mapping

Substrate

26-furostanol aldehyde (3)

PubChem ↗ Crowdsource substrate structure

GAME12

ΔMass: no_smiles Missing dual SMILES or RDKit not validated

Product

solasodine (6)

PubChem ↗ C[C@@H]1CC[C@@]2([C@H]([C@H]3[C@@H](O2)C[C@@H]4[C@@]3(CC[C@H]5[…

Evidence trail

Excerpts are machine-extracted plain text for biochemical provenance. Follow DOI / PubMed links for the primary literature; publisher figures and PDF images are not displayed here.

Source text excerpt Other; Other; Coupled in vitro assay with GAME4 and GAME12 using protodioscin as substrate; solasodine formed via spontaneous cyclization of 26-aminofurostanol.

Reaction & quality gates

Mechanism: Other
Evidence type: In vitro
Confidence: High
Data tier: Silver
mass=no_smiles; incomplete_SMILES
Substrate class: Other
Product class: Other

Literature & public identifiers

PubMed: PMID:39271954 ↗
DOI: 10.1038/s41589-024-01735-w ↗
UniProt: —
GenBank: —
NCBI TaxID: 4081 ↗

Incorporation of nitrogen in antinutritional Solanum alkaloid biosynthesis.

Evidence trail

Reaction & quality gates

Literature & public identifiers

Other reactions by this enzyme