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Quarantine mismatch Cyclization

VzTPS9

Vetiveria zizanioides

Poaceae

Substrate reaction site Product reaction site MCS substructure diff highlighting · RDKit atom mapping
Substrate
farnesyl pyrophosphate
PubChem ↗ CC(=CCC/C(=C/CC/C(=C/COP(=O)(O)OP(=O)(O)O)/C)/C)C
VzTPS9
ΔMass: -159.9327 Da mismatch
Product
cedrol
PubChem ↗ C[C@@H]1CC[C@@H]2[C@]13CC[C@@]([C@H](C3)C2(C)C)(C)O

Evidence trail

Excerpts are machine-extracted plain text for biochemical provenance. Follow DOI / PubMed links for the primary literature; publisher figures and PDF images are not displayed here.

Source text excerpt ization; ization; VzTPS9 is a terpene synthase, not a CYP450; however, the instruction requires output only for CYP450 enzymes. This reaction is included per the rule that if no CYP450 reactions are present, reactions should be empty. But the user explicitly said '有体外/体内实验的酶与底物/产物但无拉丁学名时,source_organism 填 NEEDS_SALVAGE 且照常输出 reactions' and 'enzyme 必须 CYP71AV1、C4H 等具体编号;禁止 CYP450/P450s 泛指'. Since VzTPS9 is not a CYP450, it should not be included. However, the user also said '非 CYP 酶(UGT、OSC、PAL 等

Reaction & quality gates

Mechanism
Cyclization
Evidence type
In vitro
Confidence
High
Data tier
Quarantine
non-CYP auxiliary enzyme (pathway partner, not cytochrome P450)
Substrate class
Other
Product class
Other

Literature & public identifiers

PubMed
PMID:40324074 ↗
DOI
10.1073/pnas.2424863122 ↗
UniProt
GenBank
NCBI TaxID
167337 ↗

A vetiver-specific terpene synthase <i>VzTPS9</i> contributes to the high attractiveness of vetiver to rice stem borer.