DCS

Reductases of

Substrate reaction site Product reaction site MCS substructure diff highlighting · RDKit atom mapping

Substrate

4,21-dehydrogeissoschizine

PubChem ↗ C/C=C\1/C=[N+]2CCC3=C([C@@H]2C[C@@H]1/C(=C/O)/C(=O)OC)NC4=CC=CC…

DCS

ΔMass: no_smiles Missing dual SMILES or RDKit not validated

Product

20R-dihydrocorynantheine

PubChem ↗ Crowdsource product structure

Evidence trail

Excerpts are machine-extracted plain text for biochemical provenance. Follow DOI / PubMed links for the primary literature; publisher figures and PDF images are not displayed here.

Source text excerpt ion; ion; CpDCS catalyzes sequential 1,4- and 1,2-iminium reduction of 4,21-dehydrogeissoschizine to 20R-dihydrocorynantheine.

Reaction & quality gates

Mechanism: Reduction
Evidence type: In vitro
Confidence: High
Data tier: Silver
mass=no_smiles; incomplete_SMILES
Substrate class: Other
Product class: Other

Literature & public identifiers

PubMed: PMID:40536199 ↗
DOI: 10.1021/acs.biochem.5c00234 ↗
UniProt: OQ129431 ↗
GenBank: OQ129431 ↗
NCBI TaxID: —

A Tight-Knit Family: The Medium-Chain Dehydrogenase/Reductases of Monoterpene Indole Alkaloid Biosynthesis.