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Silver no_smiles Reduction

WS

Gumlich aldehyde

Substrate reaction site Product reaction site MCS substructure diff highlighting · RDKit atom mapping
Substrate
18-OH-norfluorocurarine
PubChem ↗ Crowdsource substrate structure
WS
ΔMass: no_smiles Missing dual SMILES or RDKit not validated
Product
Wieland-Gumlich aldehyde
PubChem ↗ C1CN2CC3=CCO[C@H]([C@@H]4[C@H]3C[C@H]2[C@@]15[C@H]4NC6=CC=CC=C5…

Evidence trail

Excerpts are machine-extracted plain text for biochemical provenance. Follow DOI / PubMed links for the primary literature; publisher figures and PDF images are not displayed here.

Source text excerpt ion; ion; SnvWS catalyzes 1,2-iminium reduction of 18-OH-norfluorocurarine to Wieland-Gumlich aldehyde.

Reaction & quality gates

Mechanism
Reduction
Evidence type
In vitro
Confidence
High
Data tier
Silver
mass=no_smiles; incomplete_SMILES
Substrate class
Other
Product class
Other

Literature & public identifiers

PubMed
PMID:40536199 ↗
DOI
10.1021/acs.biochem.5c00234 ↗
UniProt
OM304294 ↗
GenBank
OM304294 ↗
NCBI TaxID

A Tight-Knit Family: The Medium-Chain Dehydrogenase/Reductases of Monoterpene Indole Alkaloid Biosynthesis.