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Quarantine mismatch Cyclization

CkTPS10

Curcuma kwangsiensis

Zingiberaceae

Substrate reaction site Product reaction site MCS substructure diff highlighting · RDKit atom mapping
Substrate
farnesyl pyrophosphate
PubChem ↗ CC(=CCC/C(=C/CC/C(=C/COP(=O)(O)OP(=O)(O)O)/C)/C)C
CkTPS10
ΔMass: -177.9432 Da mismatch
Product
α-copaene
PubChem ↗ CC1=CC[C@H]2[C@H]3[C@@H]1[C@@]2(CC[C@H]3C(C)C)C

Evidence trail

Excerpts are machine-extracted plain text for biochemical provenance. Follow DOI / PubMed links for the primary literature; publisher figures and PDF images are not displayed here.

Source text excerpt ization; ization; Heterologous expression in Saccharomyces cerevisiae with FPP substrate; GC-MS identified α-copaene as a major product.

Reaction & quality gates

Mechanism
Cyclization
Evidence type
In vivo
Confidence
High
Data tier
Quarantine
non-CYP auxiliary enzyme (pathway partner, not cytochrome P450)
Substrate class
Other
Product class
Other

Literature & public identifiers

PubMed
PMID:41415678 ↗
DOI
10.3389/fpls.2025.1703946 ↗
UniProt
GenBank
NCBI TaxID
136216 ↗

Integration of metabolomics and transcriptomics unravels the identification of <i>TPS</i> gene family and functional characterization of a sesquiterpenoid synthesis gene in <i>Curcuma kwangsiensis</i>.