CYP88AB3

Gynostemma pentaphyllum CYP88A

Cucurbitaceae

Substrate reaction site Product reaction site MCS substructure diff highlighting · RDKit atom mapping

Substrate

dammarenediol-II

PubChem ↗ CC(=CCC[C@@](C)([C@H]1CC[C@@]2([C@@H]1CC[C@H]3[C@]2(CC[C@@H]4[C…

CYP88AB3

ΔMass: +15.9949 Da hydroxylation(+15.9949)

Product

protopanaxadiol (PPD)

PubChem ↗ CC(=CCC[C@](C)([C@H]1CC[C@@]2([C@@H]1[C@@H](C[C@H]3[C@]2(CC[C@@…

Evidence trail

Excerpts are machine-extracted plain text for biochemical provenance. Follow DOI / PubMed links for the primary literature; publisher figures and PDF images are not displayed here.

Source text excerpt ation; ation; In vivo experiments in N. benthamiana and S. cerevisiae confirmed C-12 hydroxylation. Also confirmed by VIGS in G. pentaphyllum.

Reaction & quality gates

Mechanism: Hydroxylation (+15.99 Da)
Evidence type: In vivo
Confidence: High
Data tier: Gold
Latin binomial + experiment + dual SMILES + ΔMass pass
Substrate class: Other
Product class: Other

Literature & public identifiers

PubMed: PMID:41821502 ↗
DOI: 10.1111/pbi.70598 ↗
UniProt: —
GenBank: —
NCBI TaxID: 182084 ↗

Chromosome-Level Genome Assembly of the Allotetraploid Gynostemma pentaphyllum Provides Novel Insights Into the Biosynthesis of Ginsenoside and Gypenoside LVI.

Evidence trail

Reaction & quality gates

Literature & public identifiers

Other reactions by this enzyme