Silver
no_smiles
Hydroxylation
Substrate reaction site
Product reaction site
MCS substructure diff highlighting · RDKit atom mapping
CYP71BL2
ΔMass: no_smiles
Missing dual SMILES or RDKit not validated
Evidence trail
Excerpts are machine-extracted plain text for biochemical provenance. Follow DOI / PubMed links for the primary literature; publisher figures and PDF images are not displayed here.
Source text excerpt ation; ation; LsCOS catalyzes 6β-hydroxylation of GAA; product spontaneously lactonizes to costunolide.
Reaction & quality gates
- Mechanism
- Hydroxylation
- Evidence type
- In vitro
- Confidence
- High
- Data tier
- Silver
mass=no_smiles; incomplete_SMILES - Substrate class
- Organic acids
- Product class
- Organic acids
Literature & public identifiers
- PubMed
- PMID:21515683 ↗
- DOI
- 10.1074/jbc.m110.216804 ↗
- UniProt
- F8S1I0 ↗
- GenBank
- —
- NCBI TaxID
- 4236 ↗
Lettuce costunolide synthase (CYP71BL2) and its homolog (CYP71BL1) from sunflower catalyze distinct regio- and stereoselective hydroxylations in sesquiterpene lactone metabolism.